Process for the production of metal-complex carboxylic acid amid

Details Process for the production of metal-complex carboxylic acid amid Process for the production of metal-complex carboxylic acid amid

1997-12-02

2000-04-04

Hollinden, Gary E.

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Magnetic imaging agent

534 16, 540465, 540474, 556 50, 556 55, 556 63, 556 77, 556105, 556116, 556134, 556148, 514836, A61B 5055

Patent

active

060457767

ABSTRACT:
The invention relates to a process for the production of metal-complex carboxylic acid amides, characterized in that a metal-complex carboxylic acid mixture that consists of the metal-complex carboxylic acid and at least one solubilizing substance in dimethyl sulfoxide (DMSO) is pretreated with a dehydrating reagent, optionally with the addition of a coupling adjuvant, and is then reacted with an amine of general formula I

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patent: 5565184 (1996-10-01), Dunn et al.
patent: 5804163 (1998-09-01), Gibby et al.

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