Process for the production of known and new 6-amino-6-desoxy-2,3

Details Process for the production of known and new 6-amino-6-desoxy-2,3 Process for the production of known and new 6-amino-6-desoxy-2,3

1980-08-25

1984-01-31

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 175, 536 55, 536 553, 536124, 546219, 546242, C07H 1704

Patent

active

044291175

ABSTRACT:
The invention relates, inter alia, to a process for the provision of 6-amino-6-desoxy-2,3-O-isopropylidene-.alpha.-L-sorbofuranose derivatives which comprises treating a 2,3-O-isopropylidene-6-sulphonated-.alpha.-L-sorbofuranase with an amine in an aqueous medium in an autoclave, followed by reaction of the reactions product in a basic medium to provide the free amine of Formula I as described hereinafter. The invention also includes the products obtained by the reaction and the invention further includes the process for providing the compounds of Formula VII as described hereinafter by treatment of a compound of Formula I as described hereinafter with an acid, followed by hydrogenation. The products of the invention are useful as medicaments or intermediates for medicaments.

REFERENCES:
patent: 2422997 (1947-06-01), Wuest
patent: 2884411 (1959-04-01), Heyns
patent: 4220782 (1980-09-01), Stoltefuss
patent: 4260622 (1981-04-01), Junge et al.

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