Process for the production of isobutyric acid anhydride

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260544A, C07C 5154

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active

043035949

ABSTRACT:
A process for the production of isobutyric acid anhydride in which propylene is initially carbonylated in the presence of a substantial molar excess of liquid anhydrous hydrogen fluoride to provide a reaction mixture of isobutyroyl fluoride and unreacted hydrogen fluoride. Following distillation of the reaction mixture to recover a recycle stream of hydrogen fluoride, the isobutyroyl fluoride residue is partially hydrolyzed in the presence of a hydrogen fluoride acceptor resulting in a hydrolysis product consisting essentially of isobutyroyl fluoride, isobutyric acid anhydride and a hydrogen fluoride complex of said acceptor. Following removal of the solid complex, the hydrolysis product is fractionally distilled to yield an overhead fraction of isobutyroyl fluoride for reuse in the hydrolysis reaction.

REFERENCES:
patent: 2053233 (1936-09-01), Woodhouse
Komatsu et al., Bull. Jap. Pet. Inst., 16, 124-131 (1974).
Friedman et al., J. Org. Chem. 1961, vol. 26, pp. 3751-3754.

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