Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Patent
1991-04-11
1996-12-17
Guzo, David
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
435 691, 435 697, 435 698, 4351721, 4351723, 4352541, 43525411, 4352542, 43525421, 4352551, 4352552, 43525521, 4353201, 536 231, 536 234, 536 235, C12N 936, C12N 500
Patent
active
055852572
ABSTRACT:
Yeast cells whose DNA has been appropriately engineered to produce and to secrete lysozyme under control of a regulatable promoter are grown in the substantial absence of lysozyme synthesis and then are induced to produce and to secrete lysozyme under growth-limited conditions. This process is particularly suitable for the production of human lysozyme or mutants thereof.
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De Baetselier Annie
Hanotier Jacques D. V.
Rosenberg Steven
Cheairs M. Norwood
Chiron Corporation
Fina Research S.A.
Guzo David
Parkhurst Roger W.
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