Process for the production of high-purity...

Details Process for the production of high-purity... Process for the production of high-purity...

2004-05-06

2008-12-09

Richter, Johann (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

Reexamination Certificate

active

07462718

ABSTRACT:
A process for the production of high-purity rac-1-{4-[2-hydroxy-3-(5-quinolyloxy)propyl]-piperazin-1-yl}-2,2-diphenylethan-1-one fumarate as well as rac-1-{4-[2-hydroxy-3-(5-quinolyloxy)propyl]piperazin-1-yl}-2,2-diphenylethan-1-one fumarate at a purity of at least 98.55% is described.

REFERENCES:
patent: 0363212 (1990-04-01), None
patent: 0575890 (1993-12-01), None
patent: 2000281653 (2000-10-01), None
Patent Abstracts of Japan, 2000, No. 13, Feb. 5, 2001, JP 2000 281653A (Mitsui Chemicals Inc.).
Tsuneji Suzuki et al. “Structure Activity Relationship of Newly Synthesized Quinolione Derivatives for Reversal of Multidrug Resistance in Cancer” Journal of Medicinal Chemistry, American Chemical Society, 40, 13, 1997, p. 2047-2052, ISSN 0022-2623.

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