Process for the production of heparin-containing particulate pro

Details Process for the production of heparin-containing particulate pro Process for the production of heparin-containing particulate pro

1980-12-23

1985-05-21

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C08B 3710

Patent

active

045187711

ABSTRACT:
A heparin-enriched material capable of long-term storage and particularly adapted for use as a raw material in processes for the extraction of heparin is produced by storing the animal organ material for a period of 0.5 to 15 hours (preferably 4 to 6 hours) at a temperature of 10.degree. to 50.degree. C. (preferably 30.degree. to 50.degree. C.), then injecting steam to effect a heat treatment at a temperature between 75.degree. and 100.degree. C. The heat treatment precipitates heparin-containing aggregate which is filtered from the aqueous phase and dried to a dry substance content of 90 to 95%.

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patent: 4122250 (1978-10-01), Schmer
patent: 4192916 (1980-03-01), Melby et al.
patent: 4301153 (1981-11-01), Rosenberg

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