Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Patent
1997-01-17
1999-10-05
Naff, David M.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
435136, 435169, 435171, 4352551, 435261, 435822, C12N 100, C12N 102, C12P 102, C12P 742
Patent
active
059622865
ABSTRACT:
Strains of Aureobasidium pullulans (de bary) Arnaud can be used for the commercial production of gluconic acid by fermentation in aqueous liquid containing sugar, which in continuous culture from glucose form greater than or equal to 90% and greater than or equal to 90% molar selectivity. The process is conducted with an Fe and Mn optimized medium with a nitrogen-independent (N-independent) ion concentration. The iron (Fe) concentration with 3 g/l NH.sub.4 Cl is greater than or equal to 0.5 mM, and the manganese (Mn) concentration with 3 g/l NH.sub.4 Cl is greater than or equal to about 0.5 mM manganese (Mn). The pH is regulated between about 4.5 and about 8, in particular at 6.5-7, and the temperature between 24 and 32.degree. C., in particular at 29-30.degree. C. Particularly successful strains are Aureobasidium pullulans (de bary) Arnaud with the registration numbers DSM 7085, DSM 7086, DSM 7087, and DSM 7088.
REFERENCES:
patent: 4871665 (1989-10-01), Viehweg
patent: 5681732 (1997-10-01), De Graafl et al.
Su, Yuan-Chi et al., "Studies on Microbical Pred. of Sicl. Glucinate & Glucone-D-lacture from Stoids", 1977, pp. 143-160, See Abstract Only. Proc. Natl. Sci. Counc.
Ullmann's Encyclopaedia of Industrial Chemistry, 1989, vol. A12, pp. 449-455.
Perwoszwansky in Microbiology, Formation of Gluconic Acid During the Oxidation of Glucose by Bacteria, V.V. Perwoszandky, p. 149 1939.
Aivasidis Alexander
Anastassiadis Savas
Wandrey Christian
Naff David M.
Pasternack Sam
Ware Deborah K.
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