Process for the production of gamma nonalactones in natural form

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...

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435938, C12P 1708

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active

056460228

ABSTRACT:
Gamma lactones with 9 carbon atoms, saturated or unsaturated and mixtures thereof, in natural form, are obtained by:
A) culturing a microorganism selected from the group comprising Pichia ohmeri and Pichia stipitis or both of these in a substrate comprising an unsaturated C.sub.18 hydroxy-acid with the hydroxyl in position C.sub.13 to obtain a mixture comprising gamma nonanolide;
or, alternatively,
B) subjecting to lipoxygenation a substrate comprising an acid selected from the group comprising linoleic acid and linolenic acid or mixtures thereof and
distilling the product of lipoxygenation in a current of steam to obtain a mixture comprising an unsaturated gamma lactone that is gamma-2-nonenolide, gamma-2,6-nonadienolide or mixtures thereof.

REFERENCES:
patent: 4950607 (1990-08-01), Cardillo et al.
patent: 5168054 (1992-12-01), Cardillo et al.

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