Process for the production of furans and lactones from streptomy

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...

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435 74, C12P 1704, C12P 1944

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active

052524728

ABSTRACT:
It is possible with the aid of various Streptomycetes species to prepare new compounds having a furan or lactone structure. These compounds have a pharmacological, especially antibiotic, action.

REFERENCES:
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Zamojski, et al., "Synthesis of 3-Substituted Furans," Journal of Organic Chemistry, vol. 42, No. 6, pp. 1089-1090 (1977).
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Alper, et al., "Palladium-catalysed Conversion of Alkenols into Five- and Six-membered Ring Lactones at Room Temperature and Atmospheric Pressure," Journal of the Chemical Society, Chemical Communications, pp. 511-512 (1985).
Matsuda, et al., "A Simple Synthesis of a .alpha.-Ylidene .gamma.-Lactones from .gamma.-Trimethylsiloxy Nitriles," Bulletin of the Chemical Society of Japan, vol. 52, No. 8, pp. 2389-2393 (1979).
Ikariya, et al., "Regioselective Hydrogenation of Unsymmetrically Substituted Cyclic Anhydrides Catalyzed by Ruthenium Complexes with Phosphine Ligands," Bulletin of the Chemical Society of Japan, vol. 57, No. 3, pp. 897-898 (1984).
Mukaiyama, et al., "Convenient Synthesis of the Antibiotic Botryodiplodin," Chemical Abstracts, vol. 82, No. 7, p. 412 (1974).
Noyce, et al., "Transmission of Substituent Effects in Heterocyclic Systems. The Solvolysis of Substituted 3-Furyl Derivatives," J. Org. Chem., vol. 37, No. 16, pp. 2620-2625 (1972).
Summers, et al., Chemical Abstracts, No. 214382K, vol. 111, p. 579 (1989).
von L. Ettlinger, et al., "Uber die Isolierung und Charakterisierung von Acetomycin," Helvetica Chimica Acta., vol. 26, pp. 216-228 (1958).
Dunlop, et al., The Furans, ACS Monograph Series, pp. 64-79 (1953).

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