Process for the production of dry pharmaceutical forms and the t

Details Process for the production of dry pharmaceutical forms and the t Process for the production of dry pharmaceutical forms and the t

1998-09-11

2000-02-22

Kight, John

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

560 52, 514952, 514963, A61K 966, C07C 69612

Patent

active

060277475

ABSTRACT:
A process for the production of a solid dispersion of at least one therapeutic agent in a hydrophilic carrier having enhanced solubility in an aqueous media comprising dissolving at least one therapeutic agent in a volatile organic solvent containing a very hydrophilic polymer and evaporating the solvent to dryness; to form a co-precipitate of therapeutic agent and hydrophilic polymer. This invention relates to the resulting products and to their therapeutic method of use.

REFERENCES:
patent: 4895726 (1990-01-01), Curtet et al.
Sheu, M-T. et al.: Characterization and dissolution of fenofibrate solid dispersion systems. Int. J. Pharm. vol. 103, pp. 137-146, Mar. 15, 1994.

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