Process for the production of dry pharmaceutical forms and...

Details Process for the production of dry pharmaceutical forms and... Process for the production of dry pharmaceutical forms and...

2006-05-23

2006-05-23

Aulakh, Charanjit S. (Department: 1625)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

C514S169000, C514S963000

Reissue Patent

active

RE039104

ABSTRACT:
A process for the production of a solid dispersion of at least one therapeutic agent in a hydrophilic carrier having enhanced solubility in an aqueous media comprising dissolving at least one therapeutic agent in a volatile organic solvent containing a very hydrophilic polymer and evaporating the solvent to dryness to form a co-precipitate of therapeutic agent and hydrophilic polymer and the resulting products and their therapeutic method of use.

REFERENCES:
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patent: 385316 (1932-01-01), None
patent: 84468 (1982-11-01), None
Chiou, W.I. and Riegelman, S. : Pharmaceutical applications of solid dispersion systems. J. Pharmaceutical sciences. vol. 60, pp. 1281-1302, 1971.
Kassem, M.A.A. et al. : High energy states of Tolnaftate. Egypt. J. Pharm. Sci. vol. 33, pp. 267-281, 1992.
Pharmaceuticals Article. vol. 116, 1992 p. 449 Derwent 89-088668 (1 page).

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