Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined...
Patent
1991-01-15
1992-07-07
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Extract, body fluid, or cellular material of undetermined...
424 9464, 514 2, 514 21, 514866, 530855, A61K 556
Patent
active
051281481
ABSTRACT:
Disclosed is a process for the production of dried earthworm powder which comprises the steps of leaving a species of living earthworms in fresh water or a slightly acidic aqueous solution until the alimentary canal thereof is freed of soil, wet-grinding the living earthworms, and freeze-drying and then vacuum-drying the resulting suspension under a vacuum of 10 mmHg or below for 10 to 100 hours while raising the temperature stepwise from -60.degree. C. to 80.degree. C. This dried earthworm powder may be combined with pharmaceutically acceptable carriers to form pharmaceutical compositions which are useful for the treatment or prevention of hyperlipemia, diabetes, hypertension and hypotension in human beings.
REFERENCES:
patent: 3719496 (1973-03-01), Chen
patent: 4350625 (1982-09-01), Abe
patent: 4390630 (1983-06-01), Sawyer
patent: 4568545 (1986-02-01), Mihara et al.
Mihana; Reports of Special Research Project on Enviromental Science B304-R30, vol. 4, p. 108 (1986).
Mihara et al.; Acta Hematologica Japonica vol. 45, p. 503 (1982).
Ishii Yoichi
Mihara Hisashi
Eimei Company Ltd.
Robinson Douglas W.
Witz Jean C.
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