Process for the production of compounds with antiphlogistic acti

Details Process for the production of compounds with antiphlogistic acti Process for the production of compounds with antiphlogistic acti

1975-12-11

1978-08-01

Love, Ethel G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D20918

Patent

active

041042786

ABSTRACT:
Process for the production of a compound of the formula ##STR1## in which R stands for a benzyl radical or the radical ##STR2## and X is hydrogen or represents one or more substituents, wherein a compound of the formula ##STR3## is condensed with a compound of the formula ##STR4## in which R and X have the meaning indicated, at temperatures of at least 100.degree. C on an inert solvent as reaction medium, with formation of free HCl. The products are useful as intermediates for production of the corresponding indole derivatives wherein R is replaced by hydrogen or --CH.sub.2 COOH, which are antiphlogistically active compounds.

REFERENCES:
patent: 3390154 (1968-06-01), Gal
patent: 3483220 (1969-12-01), Gaines et al.
patent: 3919247 (1975-11-01), Pakula et al.

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