Process for the production of clavulanic acid

Details Process for the production of clavulanic acid Process for the production of clavulanic acid

1976-09-24

1978-08-29

Tanenholtz, Alvin E.

Textiles: fiber preparation

260307R, C12D 914

Patent

active

041101650

ABSTRACT:
A new antibacterially active agent has been isolated from Streptomyces clavuligerus. This new compound which is designated clavulanic acid has the formula (I): ##STR1## In addition to being a broad spectrum antibiotic of medium potency, clavulanic acid and its salts and esters have the ability to enhance the effectiveness of .beta.-lactam antibiotics against many .beta.-lactamase producing bacteria.

REFERENCES:
patent: 3770590 (1973-11-01), Inamine et al.
patent: 3801464 (1974-04-01), Gorman et al.
patent: 3862008 (1975-01-01), Hamill et al.

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