Process for the production of .beta.-hydroxy-.alpha.-aminocarbox

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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562570, 568489, C07C10130

Patent

active

044866003

ABSTRACT:
.beta.-hydroxy-.alpha.-aminocarboxylic acids of the formula: ##STR1## where R.sub.1 and R.sub.2 are hydrogen or an alkyl group having 1 to 10 carbon atoms are produced by hydrogenating the correspondingly substituted cyanohydrin in a water containing medium first in the presence of a hydrogenation catalyst and an acid at a temperature between -10.degree. and +40.degree. C. and a hydrogen pressure of less than 10 bar, until per mole of cyanohydrogen employed one mole of hydrogen is taken up and then employing the solution obtained as starting material for a Strecker or Bucherer synthesis of an amino acid.

REFERENCES:
Weygand, "Preparative Organic Chemistry," pp. 346-347, (1972).
"The Merck Index," pp. ONR-15, ONR-85 and ONR-86, (1976), 9th Ed.

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