Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1982-01-04
1984-10-02
Hazel, Blondel
Drug, bio-affecting and body treating compositions
Lymphokine
260112R, 424 88, A61K 39395, A61K 39385, C07G 700
Patent
active
044747560
ABSTRACT:
The present invention relates to a process for the production of anti-human protein antibody, comprising induction of the antibody production in non-human warm-blooded animal cells capable of producing said antibody by injecting into a non-human warm-blooded animal a human protein-saccharide conjugate, obtained by covalent attachment of a human protein with a saccharide, and harvesting the resulting anti-human protein antibody. The antibody, prepared according to the invention, contains an extremely higher amount of immunoglobulin G than that obtained by conventional method while it contains slight or substantially no immunoglobulin E. Therefore, the antibody can be used advantageously for diagnostic, prophylactic or therapeutic administration in the prevention and treatment of human diseases.
REFERENCES:
patent: 3639213 (1972-02-01), Ginger et al.
patent: 4041152 (1977-08-01), Chany et al.
patent: 4172124 (1979-10-01), Koprowski et al.
patent: 4185090 (1980-01-01), McIntire
patent: 4196265 (1980-04-01), Koprowski et al.
patent: 4238473 (1980-12-01), Lemieux et al.
patent: 4364935 (1982-12-01), King et al.
Svenson, S., et al., J. Immunological Methods, vol. 25, pp. 323-335, 1979.
Jorbeck, H., et al., J. Immunology, vol. 123, pp. 1376-1381, 1979.
Kohler, G., et al., "Continuous Cultures of Fused Cells Secreting Antibody of Predefined Specificity", Nature, vol. 256, pp. 495-497, (1975).
Davidson, R. L., et al., "Improved Techniques for the Induction of Mammalian Cell Hybridization by Polyethylene Glycon", Somatic Cell Genetics, vol. 2, No. 2, pp. 165-176, (1976).
Koyama Shunsaku
Mitsuhashi Masakazu
Hazel Blondel
Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
LandOfFree
Process for the production of anti-human protein antibody does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for the production of anti-human protein antibody, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the production of anti-human protein antibody will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-526364