Process for the production of aminophenylaminobenzimidazoles

Details Process for the production of aminophenylaminobenzimidazoles Process for the production of aminophenylaminobenzimidazoles

1978-09-12

1980-03-11

Trousof, Natalie

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

260559A, 260558A, C07D23518

Patent

active

041929470

ABSTRACT:
A process for the production of ##STR1## wherein R.sub.1 and R.sub.2 are the same or different and each is hydrogen, alkyl having 1-4 carbon atoms, alkoxy having 1-4 carbon atoms, chlorine or bromine, and n is 1 or 2 comprising reacting ##STR2## at -10.degree. C. to 100.degree. C. at a pH of from 1-10 to form an anilide of the formula ##STR3## and cyclizing and reducing the anilide in an aqueous alkaline medium with a sulfide reducing agent.

REFERENCES:
patent: 3624100 (1971-11-01), Frick et al.
patent: 4001268 (1977-01-01), Kovar et al.
patent: 4109093 (1978-08-01), Arsac et al.

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