Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1981-09-08
1984-04-17
Brown, Johnnie R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 22, 536 25, 536 28, 536 29, C07H 1920
Patent
active
044435940
ABSTRACT:
A process for the production of adenine ring system containing co-enzymes bound to a macro-molecular carrier comprising the steps of alkylating an adenine ring system containing co-enzyme in the 1 position with an alkylating agent containing a terminal group capable of reacting with said macro-molecular carrier selected from the group consisting of carboxyl, amine and vinyl, reacting said alkylated co-enzyme with a macro-molecular carrier having groups capable of reacting with said terminal groups, subjecting said alkylated co-enzyme bound to a macro-molecular carrier to a Dimroth rearrangement into the N.sup.6 -form of alkylation, and recovering said adenine ring system containing co-enzyme bound to a macro-molecular carrier.
REFERENCES:
patent: 3985690 (1976-10-01), Dean et al.
patent: 4008363 (1977-02-01), Re et al.
patent: 4011205 (1977-03-01), Dean et al.
patent: 4088639 (1978-05-01), Zappelli et al.
Zapelli et al., "Chem. Abst.", vol. 83, 1975, p. 55160(w).
Zapelli et al., "Chem. Abst.", vol. 86, 1977, p. 85301(x).
Brown Johnnie R.
Gesellschaft fur Biotechnologische Forschung mbH (GBF)
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