Process for the production of a viable cell culture infected by

Details Process for the production of a viable cell culture infected by Process for the production of a viable cell culture infected by

1996-05-22

1999-07-20

Lankford, Jr., Leon B.

Chemistry: molecular biology and microbiology

Virus or bacteriophage, except for viral vector or...

435239, 435325, C12N 500

Patent

active

059255552

ABSTRACT:
The present invention relates to a process for in vitro culture of cells infected by a virus associated with multiple sclerosis and to the infected cell lines thus produced. According to the invention, the process includes: a) cultivation of human cells infected by a viral strain to obtain at least one culture of primary cells infected by the viral strain, b) cultivation of non-infected human cells permissive to the viral strain to obtain at least one permissive culture, c) cocultivation of at least one sample of a culture of infected primary cells and one sample of the permissive culture to obtain a first infected derived culture, d) cultivation in series of the first infected derived culture. The invention is used in particular in the pharmaceutical diagnostics industry sector.

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De Keyser, "Autoim

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