Process for the production of a .beta.-amino alcohol

Details Process for the production of a .beta.-amino alcohol Process for the production of a .beta.-amino alcohol

1998-08-21

1999-11-30

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548229, 548215, C07D26320

Patent

active

059945559

ABSTRACT:
A process for producing 2-[3(S)-amino-2-(R)-hydroxyl-4-phenyl butyl]-N-tert,butyl decahydro-(4aS,8aS)-isoquinoline-e(S)-carboxamide of the formula (I) via 3(S)-[lower alkoxy carbonyl amino, phenoxy carbonyl amino or benzyl oxycarbonyl amino]-2-hydroxy-4-phenyl butyric acid and process for producing said acid.

REFERENCES:
patent: 5455353 (1995-10-01), Hilpert
patent: 5859248 (1999-01-01), Kottenhahn et al.
Morrison and Boyd: Organic Chemistry 30d Edition: See pp. 587 and 673: Jan. 1975.
CA Abstract No. 90:168996 (Abstract of DE 2725732 Published in 1978 (See pp. 9-12 of CAS Search Report.

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