Process for the production of...

Details Process for the production of... Process for the production of...

2007-03-13

2007-03-13

Davis, Brian (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C564S475000, C564S487000, C560S159000, C549S419000

Reexamination Certificate

active

11135647

ABSTRACT:
A new process for the production of 1-hydroxymethyl-1,3,5-triazapentane, trihydrochloride is described.

REFERENCES:
patent: 6676929 (2004-01-01), McMurry et al.
patent: 2002/0164289 (2002-11-01), McMurry et al.
patent: 3728525 (1989-03-01), None
patent: 3806795 (1989-09-01), None
patent: WO 96/23526 (1996-08-01), None
Sajiki, Hironao, et al: “Synthesis of Enantiomerically Pure 1-(R)-And 1-(S)-Hydroxymethyl-DTPA Penta-T-Butyl Esters Via Chiral Amino Alcohols” Synthetic Communications (1996) 26(13), 2511-2522 Coden: Syncav; ISSN: 0039-7911, XP009051769.
Amedio, et al. A Practical Manufacturing Synthesis of 1-(R)-Hydroxymethyl-DTPA: An Important Intermediate in the Synthesis of MRI Contrast Agents, Synthetic Communications, 29(14), pp. 2377-2391; 1999.

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