Process for the production of 7-(substituted)-9-[(substituted gl

Details Process for the production of 7-(substituted)-9-[(substituted gl Process for the production of 7-(substituted)-9-[(substituted gl

1994-09-13

1996-02-27

Kestler, Kimberly J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Tetracyclo naphthacene configured ring system having at...

5483611, 5483621, 5483731, 5483751, 548400, 548579, 548950, 548954, 548967, 549 68, 549496, 549505, 585 22, C07D20718

Patent

active

054950317

ABSTRACT:
The invention provides a process for the production of compounds of the formula: ##STR1## wherein R, R.sup.3, R.sup.4 and W are defined in the specification in which a compound of the following formula: ##STR2## is reacted with a nucleophile of the formula WH in an inert atmosphere in the presence of a polar aprotic solvent. The resulting compounds are useful as antibiotics.

REFERENCES:
Morrison and Boyd, Organic Chemistry, 4th ed, 1983, pp. 894, 898-900, 902.

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