Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1982-05-14
1984-03-13
Coughlan, Jr., Paul M.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
C07D22326
Patent
active
044366604
ABSTRACT:
The invention relates to a novel and technically advanced process for producing 5-cyano-5H-dibenz[b,f]azepine by reacting 5H-dibenz[b,f]azepine with a halocyanogen in the presence of strongly polar substances. 5-Cyano-5H-dibenz[b,f]azepine can be used as starting material for producing 5-carbamyl-10(11)-oxo-10,11-dihydro-5H-dibenz[b,f]azepine, which is known to have central-depressant, anticonvulsive and central-muscle-relaxing activity.
REFERENCES:
patent: 2762796 (1956-09-01), Morel et al.
Z. Rappaport (Ed) "The Chem. of the Cyano Group", pp. 78, 79, 256-263, Interscience, N.Y., N.Y. (1970).
Scott et al, Chem. Abst., 69, 26735t (1968).
Aufderhaar Ernst
Sprecher Klemenz
Zergenyi Janos
Ciba-Geigy Corporation
Coughlan, Jr. Paul M.
Feit Irving N.
Springer D. B.
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