Process for the production of 2,4-diamino-6-piperidinyl-pyrimidi

Details Process for the production of 2,4-diamino-6-piperidinyl-pyrimidi Process for the production of 2,4-diamino-6-piperidinyl-pyrimidi

1989-12-28

1990-09-25

Shen, Cecilia

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C07D40104

Patent

active

049594753

ABSTRACT:
Process for the production of 2,4-diamino-6-piperidinylpyridine-3-N-oxide starting from hydroxylamine and cyanamide by way of intermediate product 2,4-diamino-6-hydroxypyrimidine-3-N-oxide.

REFERENCES:
patent: 3644364 (1972-02-01), Anthony
Vito M. Campese, "Minoxidil: A Review of its Pharmacological Properties and Therapeutic Use," Drugs, vol. 22, pp. 257 to 278, (1981).
J. M. McCall, "A New Approach to Triaminopyrimidine N-Oxides", Jnl. of Org. Chem., vol. 40, No. 22, Oct. 1975, pp. 3304 to 3307.
Pharm. Ind. 46, (1984), pp. 937 to 938.
Pharm. Ind. 47, (1985), p. 506.
Merck Index, 10th edition, 6069 Minoxidil.

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