Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Patent
1989-03-17
1992-09-01
Marx, Irene
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
4352521, 435170, 435822, 562593, 562590, 2041823, 2041824, C12P 746, C12P 104, C12N 120, C07C 5142
Patent
active
051438348
ABSTRACT:
A process for producing and purifying succinic acid comprises growing a succinate salt-producing microorganism on an inexpensive substrate containing carbohydrate, other nutrients, sodium ions and tryptophan under a CO.sub.2 partial pressure until most of the carbohydrate is converted to succinate. The fermentation broth is then electrodialyzed to recover and concentrate the succinate salt in an aqueous stream which is subjected to water-splitting electrodialysis to form base and a succinic acid product. The resulting succinc acid product is treated first with a strongly acidic ion exchanger in the acid form to remove any sodium or other cations and then treated with a weakly basic ion exchanger in the free base form to remove any sulfate ions or sulfuric acid and to obtain a highly purified succinic acid product.
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Datta Rathin
Glassner David A.
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