Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex
Patent
1998-01-28
2000-07-04
Lankford, Jr., Leon B.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Conjugate or complex
424405, 514841, A61K 3578, A01N 2500
Patent
active
060835060
ABSTRACT:
A process for the preparation of spermicidal agents and other biologically active materials from neem oil or extractives by subjecting a neem feed obtained from neem oil to the step of enrichment. Such a step of enrichment is carried out in a chromatographic column containing a sorbant, and the feed is eluted with a non polar followed by a polar solvent or mixtures thereof. In accordance with one embodiment, the feed is formed by subjecting neem oil to the step of solvent partition, the precipitate being removed therefrom and the filterate forming the feed. In accordance with another embodiment, the feed is formed by adding a polar solvent to the filterate of the first embodiment, the lower layer formed therefrom being subjected to the step of distillation for removal of the solvent to obtain a feed.
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patent: 5501855 (1996-03-01), Talwar et al.
patent: 5663374 (1997-09-01), Nagasampagi et al.
Biosis Abstract 1995:39264--Anti-implantation effect of neem oil, 1995.
Devakumar Chakra
Ilavazhagan Govindaswamy
Lankford , Jr. Leon B.
National Research Development Corporation
Rories Charles C.
Spencer George H.
Tate Christopher R.
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