Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-12-16
2008-05-20
Shiao, Rei-tsang (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
active
07375233
ABSTRACT:
The present invention provides a novel and improved process for the preparation of Zonisamide and the intermediates thereof. In one aspect of the present invention, the process provides for: the preparation and isolation of a novel crystalline form of anhydrous 1,2-benzisoxazole-3-methanesulfonic acid of formula 1; the direct chlorination of the acid of formula 1 into its acid chloride of formula 2; and the in situ conversion of the intermediate acid chloride of formula 2 into Zonisamide
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Guntoori Bhaskar Reddy
Mohamed Nageib
Rey Allan W.
Weeratunga Gamini
Wolf Eckardt C. G.
Apotex Pharmachem Inc.
Hughes Ivor M.
Sarkis Marcelo K.
Shiao Rei-tsang
Sinden Kitt
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