Process for the preparation of ziprasidone

Details Process for the preparation of ziprasidone Process for the preparation of ziprasidone

2006-11-13

2009-10-27

Bernhardt, Emily (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C548S486000

Reexamination Certificate

active

07608711

ABSTRACT:
A process for the preparation of ziprasidone and a novel intermediate useful in its preparation. The process comprises the reduction of a compound (III) to give a compound (V) which is then reduced to compound (II). This is reacted with compound (IV) to give the desired compound.

REFERENCES:
patent: 4831031 (1989-05-01), Lowe et al.
patent: 2005/0282819 (2005-12-01), Graham et al.
patent: 2006/0089502 (2006-04-01), Venkataraman et al.

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