Process for the preparation of unsymmetrical dihydropyridines

Details Process for the preparation of unsymmetrical dihydropyridines Process for the preparation of unsymmetrical dihydropyridines

1988-11-23

1990-02-27

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21102

Patent

active

049047892

ABSTRACT:
In the preparation of nitrenedipine by reaction of an ylidene compound of the formula ##STR1## with an enamine compound of the formula ##STR2## the improvement which comprises effecting the reaction in the presence of a catalytic amount of diisopropylamine acetate or dimethylbenzylamine acetate. The product is produced in high yield with reduced amounts of symmetrical by-products.

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