Process for the preparation of toxoplasmas for the diagnosis of

Chemistry: analytical and immunological testing – Involving immune complex formed in liquid phase

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436543, 436811, 435 7, 435947, 424 85, 424 88, A61K 3900, A61K 4502, G01N 3354, G01N 3100

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044800436

ABSTRACT:
The invention relates to a process for obtaining preparations of toxoplasmas, improved for the diagnosis of toxoplasmosis by direct agglutination, said process comprising, in a first step, the inoculation in mice of a mixture of toxoplasmas and of sarcomatous cells, in a second step the inoculation in other mice of a mixture of sarcomatous cells infected with toxoplasmas coming from the mice of the first step and of non-infected sarcomatous cells, and finally the collection of the ascitic exsudate of these latter mice from 48 to 72 hours after inoculation.

REFERENCES:
Ardoin et al., CR Soc de Biol., (Paris), vol. 160, Oct. 1966, pp. 1821-1823.
Ardoin et al., CR Soc de Biol., (Paris), vol. 161, Jan 1967, pp. 117-119.
Fulton, Lancet, ii, 1959, pp. 1068-1069.
Novel, "Toxoplasmose: Vers une Clarification et une Synthese des Examens de Laboratoire", Le Quotidien du Medeein, vol. 2834, 1982, pp. 12-14.
Camargo, Inf and Immunity, vol. 21, Jul. 1978, pp. 55-58.
Shirahata, Chem. Abs., vol. 82, 1975, Ab. No. 29514z.

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