Process for the preparation of thrombin-like enzymes from snake

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C07G 7026

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active

041371275

ABSTRACT:
A process for the preparation of thrombin-like proteolytic enzymes from snake venoms or fractions thereof comprising contacting the snake venom or fraction thereof with heparin insolubilized by reaction with a water-insoluble carrier in order to bind the thrombin-like enzyme to the insolubilized heparin, removing the undesirable accompanying substances of the snake venom and splitting the thrombin-like enzyme from the insolubilized heparin.

REFERENCES:
patent: 3849252 (1974-11-01), Percs et al.
Methods in Enzymology, vol. 19, pp. 715-722 (1970).

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