Process for the preparation of thienopyridine derivatives

Details Process for the preparation of thienopyridine derivatives Process for the preparation of thienopyridine derivatives

1978-06-06

1979-11-13

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424256, C07D49504

Patent

active

041744489

ABSTRACT:
This invention relates to a process for the preparation of compounds having the general formula: ##STR1## in which: R.sub.1 represents a hydrogen atom, an optionaly substituted alkyl, aryl or aralkyl radical; R.sub.2 and R.sub.3 are the same or different and represent independently a hydrogen atom, a lower alkyl, aryl or heterocyclic radical; and R.sub.4 represents a hydrogen atom or an alkyl, cycloalkyl, alkoxy carbonyl, carboxy, aryl or heterocyclic radical, comprising reacting a compound having the formula: ##STR2## in which R.sub.1, R.sub.2 and R.sub.3 are as defined above, with a compound having the formula: ##STR3## in which R.sub.4 is as defined above; X is a halogen atom, or an optionally substituted alkoxy, thioalkyl or amino group; and Y represents an optionally substituted alkoxy, thioalkyl or amino group, or a group of the formula: ##STR4## in which R is a lower alkyl or aryl radical; or both the groups X and Y, together with the carbon atom to which they are attached, form a 6-membered hexahydro-S-triazinic, trioxannic or trithianic heterocyclic nucleus, in an inert solvent, at a temperature between 0.degree. and 150.degree. C. and in an anhydrous medium, and, if desired, liberating the free base.

REFERENCES:
patent: 4051141 (1977-09-01), Castaigne
patent: 4065460 (1977-12-01), Heymes et al.
patent: 4075340 (1978-02-01), Maffrand
patent: 4076819 (1978-02-01), Maffrand

Affiliated with

Also associated with

Rating

Process for the preparation of thienopyridine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of thienopyridine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of thienopyridine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2272653