Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2008-04-29
2008-04-29
Aulakh, Charanjit S. (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C546S090000
Reexamination Certificate
active
07365201
ABSTRACT:
A process for the preparation of the boron difluoride chelate of 1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolone carboxylic acid via:(a) the reaction of 1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolone carboxylic acid ethyl ester with,(b) fluoroboric acid in the presence of poly(methylhydrosiloxane) or hexamethyldisiloxane.
REFERENCES:
patent: 4940794 (1990-07-01), Hermecz et al.
patent: 4980470 (1990-12-01), Masuzawa et al.
patent: WO 2004/101527 (2004-11-01), None
patent: WO 2005/047260 (2005-05-01), None
DiMartino Joseph
Guntoori Bhaskar Reddy
Kondamreddy Murali
Wang Zhi-Xian
Apotex Pharmachem Inc.
Aulakh Charanjit S.
Hughes Ivor M.
Hughes Neil
Ng-Cheng-Hin Francis
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