Process for the preparation of Tazarotene

Details Process for the preparation of Tazarotene Process for the preparation of Tazarotene

2007-09-25

2007-09-25

Morris, Patricia L. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

11368486

ABSTRACT:
Tazarotene is prepared by deoxygenation of the corresponding S-oxide, in turn obtained according to two alternative synthetic pathways.

REFERENCES:
Still et al., “Thiophosphoryl bromide etc.,” CA 92:41493 (1979).
Nagasawa et al., “Organosulfur chemistry, etc.,” CA 108: 75185 (!987).
Frigoli et al., “A Practical and, etc.,” Organic Process Research & Development 2005, 9, 646-650.

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