Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...
Patent
1980-01-14
1982-09-28
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Identification or warning feature
Taste or smell or chemical irritation to the eye, nose, or...
424 22, A61K 922, A61K 924, A61K 952
Patent
active
043518257
ABSTRACT:
A process for the preparation of matrix-type tablets with retarded liberation of the active agent. The liberation of the active agent from the tablets takes place at a speed that has been adjusted precisely in advance. In the granulation process, polymethacrylate plastics insoluble in neutral or slightly acid water either as dissolved in an organic solvent or as a water dispersion are used as the retarding matrix substance. Before the tablets are compressed, an ester of a large-molecule fatty acid or a product obtained from same by means of hydrogenation is mixed into the grain mix in order to adjust the rate of liberation of the active agent.
REFERENCES:
patent: 2987445 (1961-06-01), Levesque
patent: 3062720 (1962-11-01), Costello
patent: 3148124 (1964-09-01), Gaunt
patent: 3577512 (1968-10-01), Shepherd et al.
Marttila Esko V.
Sothmann Gunnar A.
Friedman Stanley J.
Orion-yhtyma Oy
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