Process for the preparation of surface modified solid substrates

Details Process for the preparation of surface modified solid substrates Process for the preparation of surface modified solid substrates

1989-10-12

1991-09-17

Lusignan, Michael

Coating processes

Medical or dental purpose product; parts; subcombinations;...

Particulate or unit-dosage-article base

428409, 428410, 428426, 428457, 428421, 4284231, 428447, 428500, 514 56, 514 59, A01N 102

Patent

active

050494031

ABSTRACT:
Method for surface modifying substrates characterized in absorbing on the surface of a solid substrate a polyamine of a high average molecular weight and cross-linking this with crotonaldehyde either simultaneously or by addition in separate steps to produce amino groups on the surface of the substrate, and optionally adsorbing one or several alternating layers of an anionic polysaccharide and of the said polyamine being cross-linked with crotonaldehyde, and optionally finally adsorbing the said polyamine, not cross-linked, to produce free primary amino groups by which chemical entities having a biological activity may be bound by covalent or ionic bonding.

REFERENCES:
patent: 4565740 (1986-01-01), Golander et al.

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