Process for the preparation of succinylcholine halides

Details Process for the preparation of succinylcholine halides Process for the preparation of succinylcholine halides

1992-06-24

1993-04-27

Dees, Jose G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C07C 6934

Patent

active

052064204

ABSTRACT:
Preparation of succinylcholine halides of formula I: ##STR1## by reacting dialkyl succinates with an excess dimethylaminoethanol in the presence of an alkali metal alcoholate or alkali metal amide catalyst and then reacting the resulting bis(2-dimethylaminoethyl) succinates with methyl halides.

REFERENCES:
Cheng-Hsia et al., Bull. Inst. Chem., Acad. Sinica, 26 47-54 (1979).
Chemical Abstracts 99:139354f (1983).
Phillips, J.A.C.S., 71 3264 (1949).

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