Process for the preparation of substituted tetralin and...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

Reexamination Certificate

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C562S427000, C562S426000

Reexamination Certificate

active

07576238

ABSTRACT:
The present invention relates to novel processes for the preparation of substituted tetralin and substituted indane derivatives. The present invention is further directed to novel processes for the preparation of intermediates in the preparation of the substituted tetralin and substituted indane derivatives.

REFERENCES:
patent: 6028109 (2000-02-01), Willson
patent: 6306854 (2001-10-01), Brown et al.
patent: 6750236 (2004-06-01), Urbahns et al.
patent: 7351857 (2008-04-01), Chen et al.
patent: 2002/0169192 (2002-11-01), Hayward et al.
patent: 2003/0013729 (2003-01-01), Iqbal et al.
patent: 2003/0032671 (2003-02-01), Urbahns et al.
patent: 399422 (1990-11-01), None
patent: 1285908 (2003-02-01), None
patent: WO 92/01068 (1992-06-01), None
patent: WO 95/04713 (1995-02-01), None
patent: WO 97/36579 (1997-10-01), None
patent: WO 02/028821 (2002-04-01), None
patent: WO 02/0064146 (2002-08-01), None
patent: WO 02/0064549 (2002-08-01), None
patent: WO 02/0100836 (2002-12-01), None
patent: WO 2004/037777 (2004-05-01), None
patent: WO 2004/037778 (2004-05-01), None
patent: WO 2004/037779 (2004-05-01), None
Berge et al. Journal of Pharmaceutical Sciences, 1977 vol. 66(1) p. 1-19.
Assismacopoulos-Jeannet, F. et al. “Effect of a peroxisome proliferator on β-oxidation and overall energy balance in obese (fa/fa) rats”.America Phy. Soc., 1991, pp. R278-R283.
Kliewer, S. A. et al., “Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome prolideratior-activated receptors αand γ.”Proc. Natl. Acad. Sci., 1997, vol. 94, pp. 4318-4323.
Cecchi, R. et al., “Synthesis and β-adrenergic activity of atypical β-adrenergic phenylethanolaminotetralin stereoisomers.”Eur. J. Med Chem. 1994, vol. 29, pp. 259-267.
Brown, P. J. et al., “Identification of peroxisome proliferators-activated receptor ligands from a biased chemical library”,Chem.&Bio., 1997, vol. 4, No. 12, pp. 909-918.
Brown, P. J. et al., “Generation of Secondary Alkyl Amines on Solid Support by Borane Reduction: Application to the Parallel Synthesis of PPAR Ligands”,Synthesis, 1997, pp. 778-782.
Hawke, R. L., et al., “Potent pypocholesterolemic activity of novel ureido phenoxyisobutyrates correlates with their Intrinsic fibrate potency and not with their ACAT inhibitory activity.”J. Lipid Res., 1997, vol. 38, pp. 1189-1203.
Brown, P. J., “A Ureido-Thioisobutyric Acid (GW9578) Is a Subtype-Selective PPAR α Agonist with Potent Lipid-Lowering Activity.”J. Med. Chem., 1999, vol. 42, pp. 3785-3788.
Guerre-Millo, M. et al., “Peroxisome Proliferator-activated Receptor α Activators Improve Insulin Sensitivity and Reduce Adiposity.”J. Bio. Chem., 2000, vol. 275, No. 22, pp. 16638-16642.
Brown, P. J., “Identification of a Subtype Selective Human PPAR α Agonist Through Parallel-Array Synthesis.”Bioorg. Med. Chem. Lett., 2001, vol. 11, pp. 1225-1227.
PCT International Search Report dated Sep. 28, 2005 for PCT Application No. PCT/US2005/013870, which relates to U.S. Appl. No. 11/958,618, filed herewith.

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