Process for the preparation of substituted indoles

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D20908

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active

053997140

ABSTRACT:
The invention relates to a novel process for the preparation of compounds of formula I ##STR1## wherein R is straight-chain C.sub.2 -C.sub.4 alk-1-en-1-yl, and salts thereof, and to a novel starting material and the use thereof.

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patent: 5096917 (1992-03-01), Sallman
patent: 5248693 (1993-09-01), Gerspacher
Chem Abstr vol. 100, 210430z Pozdnev, V. F., 1984.
Mattassa et al.; "Evaluation of a series of Peptido leukotriene Antagonists: Synthesis and Structure/Activity Relations of 1,3,5-substituted Indoles and Indazoles". J. Med. Chem 1990, 33, 1781-1790.
CA 106:176163b Heterocyclic amide derivatives Brown et al., p. 707, 1987.
CA116:59209s Preparation . . . agents. Sallmann et al., p. 845, 1992.
CA119:139093b Preparation . . . antagonists. Gerspacher et al., p. 864, 1993.

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