Process for the preparation of substituted 3-arylquinazoline-2,4

Details Process for the preparation of substituted 3-arylquinazoline-2,4 Process for the preparation of substituted 3-arylquinazoline-2,4

1996-05-10

1998-02-17

Grumbling, Matthew V.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

514259, C07D23996

Patent

active

057192847

ABSTRACT:
The invention relates to a process for the preparation of substituted 3-arylquinazoline-2,4-diones of the formula (I) ##STR1## in which R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as defined in claim 1 and Ar is ##STR2## where R.sup.5 to R.sup.9 are as defined in claim 1, by reacting a compound of the formula (II) ##STR3## with a compound Z in the presence of a catalyst, a ligand and a solvent, where Z is

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