Process for the preparation of substantially alcohol free pharma

Details Process for the preparation of substantially alcohol free pharma Process for the preparation of substantially alcohol free pharma

1995-01-17

1995-12-26

Bleutge, John C.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424469, 424484, 424488, 424489, 424499, A61K 914

Patent

active

054785715

ABSTRACT:
A novel process for the preparation of pharmaceutical compositions involving the stabilization of the active drug(s) through the reduction of residual alcohol present in a drug/carrier blend. The presence of residual alcohol in dried pharmaceutical compositions adversely affects many drugs which must be initially dissolved therein in order to achieve uniform distributions throughout the excipient carrier materials. Wherein not previously possible, its removal is achieved utilizing precise processing parameters in which water lost during the drying process is replenished during blending in a conventional solids processor.

REFERENCES:
patent: 4305502 (1981-02-01), Gregory et al.
patent: 4359593 (1982-11-01), Feldman
patent: 4371516 (1983-02-01), Gregory et al.
patent: 4684519 (1987-08-01), Barabas
patent: 4754597 (1988-07-01), Buxton et al.
patent: 4985252 (1991-01-01), Jung et al.
patent: 5008114 (1991-04-01), Lovrecich
patent: 5100669 (1992-03-01), Hyon
patent: 5215756 (1993-06-01), Gole et al.
patent: 5229108 (1983-07-01), Solomon
Mark et al., Kirk--Othmer Encyclopedia of Chemical Technology, vol. 3, pp. 361-363 (1978), Wiley & Sons, New York US.

Affiliated with

Also associated with

Rating

Process for the preparation of substantially alcohol free pharma does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of substantially alcohol free pharma, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of substantially alcohol free pharma will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1367383