Process for the preparation of sterile amoxycillin sodium salt

Details Process for the preparation of sterile amoxycillin sodium salt Process for the preparation of sterile amoxycillin sodium salt

1995-09-15

1996-09-24

Burn, Brian

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

514197, C07D27760

Patent

active

055592414

ABSTRACT:
A process for the preparation of sterile sodium amoxycillin characterized by the fact that a solution of amoxycillin trihydrate in a mixture of methyl alcohol and a lower C.sub.2 -C.sub.5 alcohol is reacted in a sterile ambient, optionally in the presence of a suitable amine, with a solution of a suitable salifying agent selected from the group consisting of an alcoholate or carboxylate of sodium in methyl acetate followed by separation of the precipitate is described.

REFERENCES:
patent: 3192198 (1965-06-01), Nayler et al.
patent: 4387051 (1983-07-01), Corbett et al.

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