Process for the preparation of stable radiodiagnostic products

Details Process for the preparation of stable radiodiagnostic products Process for the preparation of stable radiodiagnostic products

1989-01-31

1989-10-10

Maples, John S.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

534 14, 252404, 25240062, 562478, A61K 4902, C07F 1300, C07C14342

Patent

active

048730742

ABSTRACT:
Stable injection solutions of radiodiagnostic aids ready for use are obtained by addition to the organ- or tissue-specific carrier, before, during of after the labeling with the pertechnetate, of a compound of the formula: ##STR1## in which R denotes hydrogen, and R' denotes a sulpho- or a carboxymethyl group, or R and R' each denote a sulpho- or a carboxymethyl group, or a water-soluble salt thereof, as stabilizer. These compounds do not alter the specific organ or tissue distribution of the carrier.

REFERENCES:
patent: 4229427 (1980-10-01), Whitehouse
patent: 4440738 (1984-04-01), Fawzi et al.
patent: 4451451 (1984-05-01), Rimmer

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