Process for the preparation of spherules

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

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424490, 424491, 424451, A61K 914

Patent

active

054927013

ABSTRACT:
An oil-in-water emulsion is passed through a nozzle to form spherules which are allowed to fall countercurrent to a flow of cold air and which are recovered utilizing either a liquid crosslinking agent or a solution, preferably aqueous, optionally containing a crosslinking agent.

REFERENCES:
patent: 4670247 (1987-06-01), Scialpi
patent: 4921705 (1990-05-01), Arai et al.
patent: 5023235 (1991-06-01), N'Guyen et al.
patent: 5137725 (1992-08-01), Handjani et al.
patent: 5186948 (1993-02-01), Takei
patent: 5188838 (1993-02-01), Deleuil et al.

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