Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1980-03-03
1982-06-29
Phillips, Delbert R.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
2601125R, C07C10352
Patent
active
043371949
ABSTRACT:
The present invention relates to a new process for the stepwise preparation of somatostatin enabling a product of high purity to be obtained, with high yields, from cysteine in 14 position whose acid function is protected by the phenylazobenzylsulfonylethyloxy group and thiol function is protected by the acetamidomethyl group, all the peptide coupling reactions being effected in liquid phase in the dimethylformamide, the intermediate peptides being precipitated by addition of a second solvent and purified in solid phase by washing with the aid of suitable solvents dissolving the impurities.
REFERENCES:
patent: 3917578 (1975-11-01), Immer et al.
patent: 3917581 (1975-11-01), Immer et al.
patent: 4216141 (1980-08-01), Rivier et al.
Diaz Joseph
Guegan Remy
C. M. Industries
Eslinger Lewis H.
Phillips Delbert R.
LandOfFree
Process for the preparation of somatostatin does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for the preparation of somatostatin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of somatostatin will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2164395