Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-04-17
2007-04-17
Seaman, D. Margaret (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
active
10539736
ABSTRACT:
A process for manufacturing simvastatin is provided using novel intermediates. Thus, for example, lovastatin is reacted with methoxyethylamine, alpha methylated 2-methylbutyryl side chain of the amide formed, hydrolyzed and lactonized to produce finally simvastatin of high purity.
REFERENCES:
patent: 5462933 (1995-10-01), Kramer et al.
patent: 5763646 (1998-06-01), Kumar et al.
patent: 6603022 (2003-08-01), Sambasivam et al.
Muralidhara Reddy Dasari
Parthasaradhi Reddy Bandi
Raji Reddy Rapolu
Rathnakar Reddy Kura
Reddy Kesireddy Subash Chander
Caesar Rivise Bernstein Cohen & Pokotilow Ltd.
Hetero Drugs, Ltd.
Rahmani Niloofar
Seaman D. Margaret
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