Process for the preparation of ribonucleotide reductase inhibito

Details Process for the preparation of ribonucleotide reductase inhibito Process for the preparation of ribonucleotide reductase inhibito

1996-07-30

1998-06-02

Wilson, James O.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 2852, 536 275, C07H 100

Patent

active

057602107

ABSTRACT:
The present invention is directed toward a novel process of preparing 2'-exocyclic vinylfluoride derivatives of cytidine analogues for use as ribonucleotide reductase inhibitors.

REFERENCES:
patent: 5047520 (1991-09-01), Matsuda et al.
patent: 5378693 (1995-01-01), McCarthy et al.
patent: 5589587 (1996-12-01), McCarthy et al.
McCarthy, et al., J. of the American Chemical Society 113(19); 7439-7440 (1991).
Takenuki, et al., J. Med. Chem. 31: 1064-1066 (1988).
McCarthy, et al., Tetrahedron Letters 31(38):5449-5452 (1990).
Sabol, et al., Tetrahedron Letters 33(22):3101-3104 (1992).
Matsuda, et al., Chem. Pharm. Bull. 36(3):945-953 (1988).
Markiewicz et al., Tetrahedron Letters, vol. 29, No. 13:1561-1564 (1988).

Affiliated with

Also associated with

Rating

Process for the preparation of ribonucleotide reductase inhibito does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of ribonucleotide reductase inhibito, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of ribonucleotide reductase inhibito will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1461347