Process for the preparation of racemic...

Details Process for the preparation of racemic... Process for the preparation of racemic...

2004-06-16

2008-09-30

Parsa, Jafar (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C556S400000, C556S427000, C558S044000

Reexamination Certificate

active

07429675

ABSTRACT:
The present invention provides a process for the preparation of substantially racemic 2-{[2-(4-hydroxyphenyl)ethyl]thio}-3-[4-(2-{4-[(methylsulfonyl)oxy]phenoxy}ethyl)phenyl]-propanoic acid which comprises reacting 2-{[2-(4-hydroxyphenyl)ethyl]thio}-3-[4-(2-{4-[(methylsulfonyl)oxy]phenoxy}ethyl)phenyl]propanoic acid enriched in one enantiomer with a base in an inert solvent.

REFERENCES:
patent: 4918196 (1990-04-01), Doya et al.
patent: 61197530 (1986-09-01), None
patent: WO 95/21162 (1995-08-01), None
patent: WO 99/62871 (1999-12-01), None
patent: WO 99/62872 (1999-12-01), None
patent: WO 03/051826 (2003-06-01), None

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