Process for the preparation of (R)-3-hexyl-5,6-dihydro-4-hydroxy

Details Process for the preparation of (R)-3-hexyl-5,6-dihydro-4-hydroxy Process for the preparation of (R)-3-hexyl-5,6-dihydro-4-hydroxy

1993-10-04

1995-05-30

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549294, C07D30932

Patent

active

054203058

ABSTRACT:
A process for the preparation of a tautomeric mixture of compounds of the formulas ##STR1## wherein W is hydrogen or C.sub.6 H.sub.13, which comprises treating a compound of the formula ##STR2## wherein R is unsubstituted or substituted alkoxy, arylalkoxy, aryloxy or amine and R.sup.1 is hydrogen or when R is alkoxy, substituted alkoxy, substituted amine, unsubstituted or substituted arylalkoxy R.sup.1 can also be metal, with a compound of the formula ##STR3## wherein W is as described above, both X and Y are reducible groups or X is hydrogen and Y is a reducible group or Y is hydrogen and X is a reducible group and, Z is hydroxy or a leaving group to form the compound of formula IV ##STR4## wherein W, X, Y and R are as defined above, the compound of formula IV is treated with a low valent metal to form a tautomeric mixture of compounds of formulas I and Ia, which are useful in the synthesis of tetrahydrolipstatin.

REFERENCES:
patent: 2542849 (1948-10-01), Glahn et al.
patent: 4206222 (1980-06-01), Valetas
patent: 5245056 (1993-09-01), Karpf et al.

Affiliated with

Also associated with

Rating

Process for the preparation of (R)-3-hexyl-5,6-dihydro-4-hydroxy does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of (R)-3-hexyl-5,6-dihydro-4-hydroxy, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of (R)-3-hexyl-5,6-dihydro-4-hydroxy will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-363379