Process for the preparation of pyrrolo-quinoline quinone

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...

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435118, 435143, 4352521, 435822, 435824, 435874, C12P 1718, C12P 1716, C12N 120

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053447689

ABSTRACT:
Pyrrolo-quinoline quinone (PQQ) is microbiologically produced by culturing a bacterium in a medium containing methanol, methylamine or a mixture thereof as a carbon source and recovering PQQ from the culture medium. The bacteria are strains of Methylobacterium, Ancylobacter, Hyphomicrobium, Xanthobacter, Thiobacillus, Microcyclus and Achromobacter.

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Ameyama et al, Agric Biol Chem vol. 48, pp. 561-565, 1984.
Patel et al, Dev. Ind. Microbiol. 1982, vol. 23, pp. 187-205.
de Beer et al, Biochim. Biophys. Acta. vol. 622, 1980, pp. 370-374.
Bergey's Manual 1974, pp. 268-269.
Bergeys Manual 1984, pp. 133-135.
Duine et al, Biochim. Biophys Acta vol. 524, 1978, pp. 277-287.
Duine et al. TIBS, vol. 6, pp. 278-280, 1981.

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